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KMID : 0378019690120020041
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New Medical Journal
1969 Volume.12 No. 2 p.41 ~ p.44
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Clinical Observations on the Effect of Lucidiril in Neurosurgical Disease
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蔡進/Chae, Jin
朴孝一/崔德永/沈輔星/Park, Hyo Il/Choi, Duck Young/Sim, Bo Sung
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Abstract
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This study is intended to investigate the effect of Lucidril (Meclofenoxate,. hydrochloride) on the neurosurgical patients.
Lucidril was given intravenously, in a dose of 250-125 mg daily for about 7-14 days, to 20 cases of severe craniocerebral injury, 3 cases of cerebral infarction, 2 cases of intracerebral hematorna, one case of meningioma and one severe cerebral hypoxia case due to hemorrhagic shock.
The results were as follows:
In craniocerebral injury group Lucidril was seemed to be has excellent effect in improvement of unconsciousness except in 15% who had diffuse severe contusion.
In cerebral infarction group Lucidril was effective in improving consciousness, mental state, speech disturbance and other neurological deficit in all cases.
For postoperative unconsciousness in 2 cases of intracerebral hematoma and one case of meningima, and for an unconsciousness case due to severe hemorrhagic shock Lucidril had dramatic effect.
Electroencephalographic study was performed in all cases and fopnd in 12 cases of these excellent improvement in 59% and moderate improvement in 33% following the treatment of Lucidril
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